In the game MoNoPOLi (Molybdenum, Nobelium, Polonium, Oxygen, Lithium), players try to acquire complete sets of element groups including alkaline Earth metals, d-transition metals and halogens, while answering questions regarding lab ware, chemical principles, periodic table trends and more. Along the way, they try to avoid Unfavorable Enthalpy and Binding Energy and hope to land on a Reaction Pathway Shortcut.